antitumor effects — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9744	MP07-66		Phosphatase
	MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells.		Phosphatase
T60022	Aromatase-IN-2		Others
	Aromatase-IN-2 has anti-inflammatory, antitumor and antiasthmatic effects.		Others
T13111	Tegadifur	40497S,FD 1	Others
	Tegadifur (40497S) is an orally available antitumor compound with antimetabolic effects, often used with uracil and in the treatment of rectal adenocarcinoma.		Others
T9992	SphK1&2-IN-1		S1P Receptor
	SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.		S1P Receptor
TMS1743	Salvigenin		MAO , Autophagy , ROS Kinase
	Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.		MAO , Autophagy , ROS Kinase
T5845	7ACC1	DEAC,Coumarin D 1421,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter
	7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistan...		Monocarboxylate transporter
TN6097	Girinimbine	Girinimbin	Apoptosis , Antioxidant , Antibacterial
	Girinimbine (Girinimbin) is a carbazole alkaloid isolated from the plants M. koenigii, M. koenigii and Murraya koenigii.Girinimbine has a wide range of biological effects, including apoptosis, antitrypanosomal, antiplate...		Apoptosis , Antioxidant , Antibacterial
T12971	Solanidine		Others
	Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.		Others
T23911	CPS-11	CPS11,CPS 11,N-(Hydroxymethyl)thalidomide	Dehydrogenase , NF-κB , Reactive Oxygen Species
	CPS-11 (N-(Hydroxymethyl)thalidomide) is a Thalidomide analogue that has significant antitumor activity and exhibits a wider range of activity and highly potent effects on the MM (multiple myeloma) cell line.		Dehydrogenase , NF-κB , Reactive Oxygen Species
T13350	Wushanicaritin		Others
	Wushanicaritin is a natural product isolated from the traditional Chinese medicine Epimedium plants, with antitumor effects and anti-inflammatory property.		Others
T16551	Pladienolide B		Apoptosis
	Pladienolide B is a potent spliceosome inhibitor, a macrolide isolated from Streptomyces obtusususus Mer-12, which targets the SF3B1 subunit of the spliceosome.Pladienolide B exerts its antitumor effects by inhibiting pr...		Apoptosis
T19768	γ-Tocotrienol	gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol	Others
	γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.		Others
T5S1607	Morusin	Mulberrochromene	NF-κB , Antibacterial , STAT
	1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti...		NF-κB , Antibacterial , STAT
TN6963	Hentriacontane		NF-κB
	Hentriacontane is a natural product.		NF-κB
T38815	Millepachine		Apoptosis
	Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.		Apoptosis
TN2326	(Z)-Butylidenephthalide	(Z)-3-Butylidenephthalide	Glucosidase
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.		Glucosidase
TN1148	Isopsoralenoside		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Antibacterial
	Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.
T3408	Syringin	Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine	NOS , Autophagy
	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.		NOS , Autophagy
T13174	TMPyP4 tosylate	TMP 1363	DNA/RNA Synthesis , Telomerase
	TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.		DNA/RNA Synthesis , Telomerase
T5771	Hypocrellin A		Antibacterial , PKC , Parasite
	Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.		Antibacterial , PKC , Parasite